Seroatlas · Human Serome Atlas

Q8N814

Putative uncharacterized protein FLJ40140

Also known as: YG045_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N814
Gene: Q8N814
Canonical length: 137 aa

OverviewNCBI Gene

No narrative summary is available for Q8N814 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

137 residues, UniProt reviewed canonical sequence.

>Q8N814|Q8N814
     1  MGWVIPEWPG AQSCPTAAQV AQPVPFMCNA PASPINDKEK DKAGGRLPSG SEPRARAFCE
    61  AGADGEQGDP SPADTIKANQ GHIPAAPGET GSVICWCDQS VAPPRPAGLS VSGRQSYLVG
   121  CFRWVLTFFF SVFYLTP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N814 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.68

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N814 as an antibody target. Whether an autoantibody or antibody against Q8N814 could matter depends on whether native Q8N814 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N814 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N814 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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