Seroatlas · Human Serome Atlas

Q8N7P7

Uncharacterized protein FLJ40521

Also known as: YH007_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8N7P7
Gene
Q8N7P7
Canonical length
452 aa

OverviewNCBI Gene

No narrative summary is available for Q8N7P7 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

452 residues, UniProt reviewed canonical sequence.

>Q8N7P7|Q8N7P7
     1  MTAVSSNRNP EDDGCLLEQE PRGRRLSPRT GTPRTTAVSS NRDPKNDGCL LKQEPRGRRL
    61  SPRTGAPGTT AVSSNRNPED DGCLLKQEPR GRRLSPQTGT PRTTAVSSNR NPGDDGCLLK
   121  QGPRGRRLSP QTGTPGTTAV SSNRNPEDDG CLLKQEPRGR RLSPQTGTPG TTAVSSNRDH
   181  EDDGCLLKQE SRGRRLSPQT GTPGTTAVSS NRNPEDDGCL LKQESRGRRL SPQTGTPGTT
   241  AVSSNRDPED DGCLLKQGPR GRRLSPQTGT PRTTAVSSNR NPEDDGCLLK QGPRGRRLSP
   301  QTGIPRTTAV SSNRDPGEDG CLLKQESRGR RLSPQTGTTR TTAVSSKRNP EDDGCLLKQE
   361  PRGRRLSSLT GAPGTTAVSS NRDPRTTAVS SNRNPGDDGC LLKQGPRGRR LSPQTGTPGT
   421  TAVSSNRDPE DDGCLLKQEP QELRKPEADT AL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N7P7 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.32

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N7P7 as an antibody target. Whether an autoantibody or antibody against Q8N7P7 could matter depends on whether native Q8N7P7 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N7P7 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N7P7 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q8N7P7. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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