Seroatlas · Human Serome Atlas

Q8N6K4

Putative uncharacterized protein MGC34800

Also known as: YP021_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N6K4
Gene: Q8N6K4
Canonical length: 173 aa

OverviewNCBI Gene

No narrative summary is available for Q8N6K4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

173 residues, UniProt reviewed canonical sequence.

>Q8N6K4|Q8N6K4
     1  MGDLPWAPPE AQAPSTAGAG DVAEHQVAPA RFLQGAWRQA AGWLCRETGA APGSAQAGPP
    61  ETAHAADPQP RGPQAPPRLP PSLSPERVHP GQPAAPAEPA PGAPALRSGP SQPRGLRLPV
   121  PVPACAGSSA PGSPAALPDS YPWPPPARNR PATLPPTSRV SPLAAFLASA PQR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N6K4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.71

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N6K4 as an antibody target. Whether an autoantibody or antibody against Q8N6K4 could matter depends on whether native Q8N6K4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N6K4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N6K4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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