Seroatlas · Human Serome Atlas

Q8N1Y9

Putative uncharacterized protein FLJ37218

Also known as: YI025_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N1Y9
Gene: Q8N1Y9
Canonical length: 231 aa

OverviewNCBI Gene

No narrative summary is available for Q8N1Y9 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

231 residues, UniProt reviewed canonical sequence.

>Q8N1Y9|Q8N1Y9
     1  MAKWVPALLL RRVPLFSLRF RPASSTFLPV LAATEPAVSV PSGDLSMPVK TRAEGEDDGF
    61  GEAGDPRRLL ERPWRFRGCL PGKGNRDVGF EGTEGPTSTR PEWVWSCRCC LGCRASTRER
   121  VTSPVRAAGP QPRFTDRETE AAAGTLAHMG FAPPTSFSHF TDQELRDCSS LECLGVVEGD
   181  PHVLCSTLSL SRPSPSATLT LLLASSCLLA PAPPSFILLL FTLIAPDLPH S

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8N1Y9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.67

OntologyGO

Cellular components

membrane

Protein domainsUniProt · Pfam · InterPro

Bublin coiled-coil protein-like, eukaryota

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8N1Y9 as an antibody target. Whether an autoantibody or antibody against Q8N1Y9 could matter depends on whether native Q8N1Y9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8N1Y9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8N1Y9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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