Seroatlas · Human Serome Atlas

Q8IZM0

Putative CNGA1-overlapping antisense gene protein

Also known as: CNG1O_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8IZM0
Gene: Q8IZM0
Canonical length: 81 aa

OverviewNCBI Gene

No narrative summary is available for Q8IZM0 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

81 residues, UniProt reviewed canonical sequence.

>Q8IZM0|Q8IZM0
     1  MDSYSAKIRA NLVCRRSTDP SIRVTFSSRS LGSLPAFAMF RSSRPSFIKI CFPFSSSIVL
    61  ASGYSVRASM RSSFERQNRS E

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q8IZM0 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q8IZM0 as an antibody target. Whether an autoantibody or antibody against Q8IZM0 could matter depends on whether native Q8IZM0 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q8IZM0 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q8IZM0 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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