Seroatlas · Human Serome Atlas

Q86TA4

Putative uncharacterized protein FLJ44553

Also known as: YB049_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q86TA4
Gene: Q86TA4
Canonical length: 180 aa

OverviewNCBI Gene

No narrative summary is available for Q86TA4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

180 residues, UniProt reviewed canonical sequence.

>Q86TA4|Q86TA4
     1  MLEGVSNEFD HFGISLPLKI CLHLGWDEGL VEGKVVRLGQ GIGKSICSSC QLFEEAPTQM
    61  STVPSGLPLP ILMHLCLLPV CMAHLCPASP CYFGATPGSG KFCRLITYSH SSPQLAASLR
   121  HRGREVGKDL PYPGLCPLTF HPSFFPPVEG CVSSLPGKLL SPQTIFFQIL WLYSKSSLVL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q86TA4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.59

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q86TA4 as an antibody target. Whether an autoantibody or antibody against Q86TA4 could matter depends on whether native Q86TA4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q86TA4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q86TA4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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