Seroatlas · Human Serome Atlas

Q6ZWC4

Putative uncharacterized protein LOC100128429

Also known as: YS043_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZWC4
Gene: Q6ZWC4
Canonical length: 215 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZWC4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

215 residues, UniProt reviewed canonical sequence.

>Q6ZWC4|Q6ZWC4
     1  MCWGKHWPRP EGRNLACSKG SPGWRTAGQG SGSYGAATLG KGTEQRGVGA LRRGLLSFTC
    61  FCLSNWTSGA GFSEMGRSRF EEGRLGYSSD VLSARPTMSP TEMLRSRALN LGAATVLRRH
   121  RAPQGTSSYQ EGRRAHEATS AESDDDNGVQ VLASLAVSCA QHSRHKDPVG TQLQQACAQV
   181  PTSRAPLWPC PSHRLMHSTD GPLDPEPLST LLPAA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZWC4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.44

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZWC4 as an antibody target. Whether an autoantibody or antibody against Q6ZWC4 could matter depends on whether native Q6ZWC4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZWC4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZWC4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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