Seroatlas · Human Serome Atlas

Q6ZVH6

Putative uncharacterized protein FLJ42569

Also known as: YK004_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6ZVH6
Gene
Q6ZVH6
Canonical length
145 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZVH6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

145 residues, UniProt reviewed canonical sequence.

>Q6ZVH6|Q6ZVH6
     1  MGPWPRDWLG KGWRLGSCEA RAGAKEVSVI RHGAPNPAQS HLHVQARAQV HSEDGHSLPP
    61  VVDGEDEVLS LLVFVQDSQE CCRQAVQGRQ GRGVTWGLGL PSYHLRTLLS PVCVPARDQR
   121  APRKCCEAVL ACPLVETLVT TLLTR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZVH6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.38

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZVH6 as an antibody target. Whether an autoantibody or antibody against Q6ZVH6 could matter depends on whether native Q6ZVH6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZVH6 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZVH6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q6ZVH6. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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