Seroatlas · Human Serome Atlas

Q6ZUG5

Uncharacterized protein FLJ43738

Also known as: YC006_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZUG5
Gene: Q6ZUG5
Canonical length: 572 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZUG5 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

572 residues, UniProt reviewed canonical sequence.

>Q6ZUG5|Q6ZUG5
     1  MPVYCKYQFH KTPVHKTKGE PHGTHVYFQD INVIFLGALH PSDLREYLEG PPMVVEVHDR
    61  DRKSEECSQK PVLFGEDPLD SYLNFQALIS PRETENNPFE SQNKMWYPYG IAQVSFADLL
   121  LGHKYLNLAV PIHSCEVQPT HCGQDSRRRK VVGLGVPRDG HQHGPMPRGN YLEADSQLKL
   181  RVDIAVPLRA GARAADPDLG GSQFGRIIFV FDFKKVSLLH SLLQDITMIN AKALGLDSYP
   241  VRTLQQILSA FKVRVRVQEQ QHLDVLTGFH LLDGKTHLFI LEGLADQGLR QLWENHQSWI
   301  PRSEHRKYKV LYNSQLLFRS RLYGDLEAIL YHVHLFQPTE LLLQQAVFFL RDTERRRVFQ
   361  ALARIHDICY NSTTLWDVTV RDLLPSSAMI KDLSQEFGMP LSQEELTDEK LFALPPQPAP
   421  NLEDYHSRNS TLTLEIHAHQ EPRKRFTYSQ DYLSAMVEPL DLKEEEKKAQ KKSRQAWLTA
   481  RGFQVTGLQS DTESSFQDLK LPPIKELNEE WKENSLFANV LEPVLDRDRW SWDRHHVDFD
   541  LYKKPPPFLE LLPSPAPKPV TVRKKKGNSP IS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZUG5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.41

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZUG5 as an antibody target. Whether an autoantibody or antibody against Q6ZUG5 could matter depends on whether native Q6ZUG5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZUG5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZUG5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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