Seroatlas · Human Serome Atlas

Q6ZTK2

Putative uncharacterized protein LOC400499

Also known as: YP015_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZTK2
Gene: Q6ZTK2
Canonical length: 550 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZTK2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

550 residues, UniProt reviewed canonical sequence.

>Q6ZTK2|Q6ZTK2
     1  MGWSDLQPAM GGEAERFQAQ LEVKLVTGGS PVVFTGNLTR QVGSKLAFSA SLSHLLSDQA
    61  NVTALLERKE ENGRRVAALG AELFVPGLVG LRALGLLQQQ GQLWTNSLRI QYSLLGQAKQ
   121  AAHECSTSQK LRADSGSDGA YRLELRHELH CTQILAFSHK VQLWHEEDSG HLHSQLEVSY
   181  GKQWDKNSNK RHLRVSQTFK NDSGPALSNH FMEFVLQVPE RQVDCRVQLY HLSLRLPYVE
   241  SSSHLKVQYN GRPLFVAGGQ WKDTSRATLW KWEGVLNLDS PWLMVSAAHR LYWPHRAVFQ
   301  AVLELTLGKA WTLKDLVVSV GCRSQGPNRE GKIQVYTAAT TYLRVSTVTV LAQSLFHSWS
   361  ELESAWNTAV QGEIHAENSR DRKILNCWLK GPQQELNLTA AYRHLEWPRK TQVSLTAVWI
   421  GAQGQPRGLQ LEGELEELRQ DRTLYRKRGA LLLRHPLHLP IPQSLLLQET FTADRRHQRY
   481  SLETRVVLNG REETLQTMVL GCQAGHPYVC AGLMHPYDGK VIPRNTEGCL VTWNQHTSLA
   541  LLSGLESGVQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZTK2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.36

Protein domainsUniProt · Pfam · InterPro

LOC400499-like
LOC400499 family

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZTK2 as an antibody target. Whether an autoantibody or antibody against Q6ZTK2 could matter depends on whether native Q6ZTK2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZTK2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZTK2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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