Seroatlas · Human Serome Atlas

Q6ZSR9

Uncharacterized protein FLJ45252

Also known as: YJ005_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6ZSR9
Gene
Q6ZSR9
Canonical length
355 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZSR9 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

355 residues, UniProt reviewed canonical sequence.

>Q6ZSR9|Q6ZSR9
     1  MGTKGLPLYP DPSRVPGTKT QNNLESDYLA RDGPSSNSSF HSSEEEGTDL EGDMLDCSGS
    61  RPLLMESEEE DESCRPPPGK LGGAVPFAPP EVSPEQAKTV QGGRKNQFQA FTQPATDGLS
   121  EPDVFAIAPF RSSRVPNDDM DIFSKAPFVS KSSMAPSQPE ESDVFLRAPF TKKKSMEELT
   181  VIQCTSQELP AQTGLLSQTG DVPLPAGRER AVYTSVQAQY STAGFVQQSN LLSHSVQAAD
   241  HLDSISPRGS CLESGGHSND RNKGPQLQKE AVSGPMAGKP FRPQSLSKYS RHYSPEDEPS
   301  PEAQPIAAYK IVSQTNKQSI AGSVSITSLS SRTTELPAAD PFALAPFPSK SGKKP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZSR9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.7

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZSR9 as an antibody target. Whether an autoantibody or antibody against Q6ZSR9 could matter depends on whether native Q6ZSR9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZSR9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZSR9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q6ZSR9. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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