Q6ZSR9
Uncharacterized protein FLJ45252
Also known as: YJ005_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for Q6ZSR9 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
355 residues, UniProt reviewed canonical sequence.
>Q6ZSR9|Q6ZSR9
1 MGTKGLPLYP DPSRVPGTKT QNNLESDYLA RDGPSSNSSF HSSEEEGTDL EGDMLDCSGS
61 RPLLMESEEE DESCRPPPGK LGGAVPFAPP EVSPEQAKTV QGGRKNQFQA FTQPATDGLS
121 EPDVFAIAPF RSSRVPNDDM DIFSKAPFVS KSSMAPSQPE ESDVFLRAPF TKKKSMEELT
181 VIQCTSQELP AQTGLLSQTG DVPLPAGRER AVYTSVQAQY STAGFVQQSN LLSHSVQAAD
241 HLDSISPRGS CLESGGHSND RNKGPQLQKE AVSGPMAGKP FRPQSLSKYS RHYSPEDEPS
301 PEAQPIAAYK IVSQTNKQSI AGSVSITSLS SRTTELPAAD PFALAPFPSK SGKKPLocalizationUniProt · AlphaFold · HPA
Whether an antibody against Q6ZSR9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.7
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads Q6ZSR9 as an antibody target. Whether an autoantibody or antibody against Q6ZSR9 could matter depends on whether native Q6ZSR9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
Q6ZSR9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label Q6ZSR9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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