Seroatlas · Human Serome Atlas

Q6ZSR3

Putative uncharacterized protein FLJ45275, mitochondrial

Also known as: YO027_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZSR3
Gene: Q6ZSR3
Canonical length: 168 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZSR3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

168 residues, UniProt reviewed canonical sequence.

>Q6ZSR3|Q6ZSR3
     1  MGWRFPSPSP RQASPVAPLL AAPTAVRSCS HCSGQREAIS SHPLQLETPE LGVCLPWHWE
    61  GWRQVRKITP SLPQPPGSQV PLEVTFHVRA TLPHFRGGET KARRAREEGK LPSLGNAPAP
   121  RRRSVAWPAA EGSCAAPESS PPASEASLPA PESSLLVAGS GDLCADSF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZSR3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.73

OntologyGO

Cellular components

mitochondrion

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZSR3 as an antibody target. Whether an autoantibody or antibody against Q6ZSR3 could matter depends on whether native Q6ZSR3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZSR3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZSR3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...