Seroatlas · Human Serome Atlas

Q6ZSN1

Putative uncharacterized protein FLJ45355

Also known as: YI023_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6ZSN1
Gene
Q6ZSN1
Canonical length
163 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZSN1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

163 residues, UniProt reviewed canonical sequence.

>Q6ZSN1|Q6ZSN1
     1  MGVPRAREGR GAGSQSPPRG RCLHPFRWGS QDRGRGEGLA LSPLLPGVPP PPAMGVPRDR
    61  GGRGAGSQST PRGGCLLPPR LGSQQPAGEE GLVLSPRLAG DASPCCDGSP KSQGVKRGWL
   121  SVPTSRGVPP PPAIGVLIAR GGRGAGSQSL PRGWSFTPLR WGS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZSN1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.76

Protein domainsUniProt · Pfam · InterPro

  • Protein of unknown function DUF4575
  • Domain of unknown function (DUF4575)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZSN1 as an antibody target. Whether an autoantibody or antibody against Q6ZSN1 could matter depends on whether native Q6ZSN1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZSN1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZSN1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q6ZSN1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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