Seroatlas · Human Serome Atlas

Q6ZSA8

Putative uncharacterized protein FLJ45684

Also known as: YS025_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZSA8
Gene: Q6ZSA8
Canonical length: 131 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZSA8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

131 residues, UniProt reviewed canonical sequence.

>Q6ZSA8|Q6ZSA8
     1  METANGEEPP AGPPVSLHGR RLLRVGGACP TPLPVLQRLP PSALHHTLHC VPRRVCVSPL
    61  GQVTRIPPVR TVRRAPSGLL PQRRGGPSWW PPSGVARGGP SWWPPSGVVR GGPSSWPPSG
   121  VAEPREALGL P

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZSA8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.73

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZSA8 as an antibody target. Whether an autoantibody or antibody against Q6ZSA8 could matter depends on whether native Q6ZSA8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZSA8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZSA8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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