Seroatlas · Human Serome Atlas

Q6ZS52

Putative uncharacterized protein FLJ45825

Also known as: YF013_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZS52
Gene: Q6ZS52
Canonical length: 159 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZS52 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

159 residues, UniProt reviewed canonical sequence.

>Q6ZS52|Q6ZS52
     1  MHQTHAIQRL EVLPSFSNES PTSRETSESW TNQDDIFYAY ASMSPGAEHR GTTQLLRFQL
    61  APIKKLEGSL QTHFLLSSLH PRMTFPGRAG GGEAGSRPPR RPWAGILILQ LPSTRGGRRS
   121  GHGAVRSWGP WKVVAEQPVG GTDPPAHGGR GRPSPNENT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZS52 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.67

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZS52 as an antibody target. Whether an autoantibody or antibody against Q6ZS52 could matter depends on whether native Q6ZS52 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZS52 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZS52 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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