Seroatlas · Human Serome Atlas

Q6ZS49

Putative uncharacterized protein FLJ45831

Also known as: YQ050_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZS49
Gene: Q6ZS49
Canonical length: 121 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZS49 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

121 residues, UniProt reviewed canonical sequence.

>Q6ZS49|Q6ZS49
     1  MEISCTSQGF FFLKEHSSGV SSVKAAQMPG RTLYRSLCSC VFPLHSPTRP PSPASAPKGF
    61  LLLSPTSSNA SKLMPYYLFH RSRGVDNSKI SVLILLGCEL EQTKKKKLGP ATALGNSGRV
   121  E

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZS49 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.49

OntologyGO

Cellular components

extracellular space

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZS49 as an antibody target. Whether an autoantibody or antibody against Q6ZS49 could matter depends on whether native Q6ZS49 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZS49 is annotated as secreted, so native Q6ZS49 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label Q6ZS49 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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