Seroatlas · Human Serome Atlas

Q6ZS46

Putative uncharacterized protein FLJ45840

Also known as: YF009_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZS46
Gene: Q6ZS46
Canonical length: 218 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZS46 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

218 residues, UniProt reviewed canonical sequence.

>Q6ZS46|Q6ZS46
     1  MQTCSGKGIK MAFLDVQSSS TPQSLPLLLF SHREGGGRGA GDPGAPAVVP APVSAPRPAS
    61  SPARSESRSP PLTLISRHIT CCSCESPGDV LLSGRGGGGG GGGGARTGGG EGEDRRPRPD
   121  FSRVTAVAIP GWMEVESPPH PPPQPQVCPT PSQGAPGHGR AGLPEGKGPG GRDWLRSQSS
   181  RCSRATLFGH RAPSPAAPRR GRLPAPGFPS LHSAVSLF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZS46 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZS46 as an antibody target. Whether an autoantibody or antibody against Q6ZS46 could matter depends on whether native Q6ZS46 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZS46 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZS46 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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