Seroatlas · Human Serome Atlas

Q6ZRU5

Putative uncharacterized protein FLJ46089

Also known as: YQ032_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZRU5
Gene: Q6ZRU5
Canonical length: 148 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZRU5 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

148 residues, UniProt reviewed canonical sequence.

>Q6ZRU5|Q6ZRU5
     1  MRCVTRTRNW WRRAARMPRA GSSAWWVAVC KQVCTRVGTY AVCWCSWNTG RFTGCPSWKD
    61  FWKPVGPALH VFNVKCEAQR GLKLTQPFTV ACKIDPVLCK SGLGFPPQLF TGCVYLSTYT
   121  YPWQAQAECV RCPRDSNRCK RITPSACL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZRU5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.43

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZRU5 as an antibody target. Whether an autoantibody or antibody against Q6ZRU5 could matter depends on whether native Q6ZRU5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZRU5 is annotated as secreted, so native Q6ZRU5 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label Q6ZRU5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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