Q6ZRG5
Putative uncharacterized protein FLJ43944
Also known as: YQ015_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for Q6ZRG5 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
221 residues, UniProt reviewed canonical sequence.
>Q6ZRG5|Q6ZRG5
1 MMRWNFSPED LSSIFRNNST LPKITVKNVD IEFTIPTAVT IEVEPSPVQQ DNPPISSEQA
61 DFSLAQPDSP SLPLESPEES ESSAQQEATA QTPNPPKEVE PSPVQQEFPA EPTEPAKEVE
121 PSATQQEASG HPLKSTKEVN PPPKQEIPAQ PSEPPEKVEL SPVLQQAPTQ LLEPLKKVEC
181 SPVQQAVPAQ SSEPSIVVEP SPVQQIAHLC LQSSLRKWNP LLocalizationUniProt · AlphaFold · HPA
Whether an antibody against Q6ZRG5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.66
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads Q6ZRG5 as an antibody target. Whether an autoantibody or antibody against Q6ZRG5 could matter depends on whether native Q6ZRG5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
Q6ZRG5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label Q6ZRG5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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