Seroatlas · Human Serome Atlas

Q6ZR54

Putative uncharacterized protein FLJ46641

Also known as: YN009_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6ZR54
Gene
Q6ZR54
Canonical length
194 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZR54 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

194 residues, UniProt reviewed canonical sequence.

>Q6ZR54|Q6ZR54
     1  MGKLRPSRGR GFADVSQQIR VRNRPSWACR RGGPLGTLLA NAGPSTVPVT PTAGSCQPSP
    61  LSPGGSDPPP PPRAHVSPQE APLGQVPGAE WLPPTRGLLC KDVSSSPGPS FHLGGPGLPG
   121  HAGPCGPRAR PAQGLAGRGG NVGEGSESPL GTLPCSVPAS QQLLRGRSHL QGSLAALGEA
   181  RGGGAAFSWG QEGP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZR54 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.72

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZR54 as an antibody target. Whether an autoantibody or antibody against Q6ZR54 could matter depends on whether native Q6ZR54 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZR54 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZR54 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q6ZR54. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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