Seroatlas · Human Serome Atlas

Q6ZR03

Uncharacterized protein FLJ46757

Also known as: YU004_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6ZR03
Gene
Q6ZR03
Canonical length
302 aa

OverviewNCBI Gene

No narrative summary is available for Q6ZR03 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

302 residues, UniProt reviewed canonical sequence.

>Q6ZR03|Q6ZR03
     1  MPCRLLHQRE TRSGGPRGPR HSAPTGPGWH NAPTLQSWEE SHAPSRDPRD HQGSVEDTSL
    61  GGDAPADGVS PSVPPLQGLG KAAGPGGTGQ AECQVVVATH RANLKPWDGR AAPLGKRTEE
   121  GRLSTSSCAS VSRNKPDSVP QGDPVWPPES TGPALCAGEE TEPQSSEGLA WGPWAQPWAP
   181  SLCPSQTGTA STASPQRASR LALQGPPGTI LSLSSSSPCL PPSHCDPGAA SSWAGLQSLK
   241  LLLQVSFQGA ADGCSLRDAN TNRKGPMHGS DFPPRLCLHS MSLWGSWGSR PPSPAHSREV
   301  AS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6ZR03 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.68

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6ZR03 as an antibody target. Whether an autoantibody or antibody against Q6ZR03 could matter depends on whether native Q6ZR03 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6ZR03 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6ZR03 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/Q6ZR03. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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