Seroatlas · Human Serome Atlas

Q6AWC8

Putative uncharacterized protein LOC100129027

Also known as: YK026_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6AWC8
Gene: Q6AWC8
Canonical length: 147 aa

OverviewNCBI Gene

No narrative summary is available for Q6AWC8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

147 residues, UniProt reviewed canonical sequence.

>Q6AWC8|Q6AWC8
     1  MYWQNWTHNG RLWGAGVHLY LSRKQCALKN TSLSKFQTSH ICKGSALQPQ QASPGASSFL
    61  TCPELGVMYL KLVLGQMVQA VRRDSGLQPF GSLFLLITQK RAVLTPFLTK TWHSLRALVY
   121  RVWSLEESRY LQREKGLVDS FGVLWEE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q6AWC8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.37

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q6AWC8 as an antibody target. Whether an autoantibody or antibody against Q6AWC8 could matter depends on whether native Q6AWC8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q6AWC8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q6AWC8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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