Seroatlas · Human Serome Atlas

Q499Y3

Putative uncharacterized protein C10orf88-like

Also known as: YJ016_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q499Y3
Gene: Q499Y3
Canonical length: 187 aa

OverviewNCBI Gene

No narrative summary is available for Q499Y3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

187 residues, UniProt reviewed canonical sequence.

>Q499Y3|Q499Y3
     1  MRAVSANYST GSPAVKSRIE LDRIQTIMES MGSKLSPGAQ QLINMVRFQQ WNCIPIEEQL
    61  QLVLGNAGYK QMTGLQCSSA LGALDKLSST PFPFRTGLTS GNVTENLQAY IDKSTQASSG
   121  ENSTKLDECK IVPQNHSLLE NDLKNATSPF LPKKANDNSN IPNSELLPFL QNLCSQVNYL
   181  LVGRKAE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against Q499Y3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

Protein domainsUniProt · Pfam · InterPro

ATPase PAAT-like

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads Q499Y3 as an antibody target. Whether an autoantibody or antibody against Q499Y3 could matter depends on whether native Q499Y3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

Q499Y3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label Q499Y3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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