Seroatlas · Human Serome Atlas

PSMG3-AS1

Putative uncharacterized protein PSMG3-AS1

Also known as: K1908_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q96PY0
Gene
PSMG3-AS1
Canonical length
264 aa

OverviewNCBI Gene

No narrative summary is available for PSMG3-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

264 residues, UniProt reviewed canonical sequence.

>Q96PY0|PSMG3-AS1
     1  MMDCTWTLPG MRATWQPAPF LPWDQTPWRV SFSWSPVLLA WGGVWSGEAH PCAHVLRPPA
    61  SPCPPRPRRG CGDSGSSGMA QRAQAGSNQS RGKCGRDGRC PPRSSPGAPE AAERVESAET
   121  RGPGKSWILS PSSMSEPRRG KARRSPGRRR HPHSSFPQAS SPSSPSRRET IPQVQSSGVP
   181  GAMSPEQTLF SRSPRGLSHL GQSLCRTVKE SEAQRGKTMP PGSHSPSGAG QGRTARKGPA
   241  REEIPSSDSS AKPSVYPHPH LTAT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PSMG3-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.67

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PSMG3-AS1 as an antibody target. Whether an autoantibody or antibody against PSMG3-AS1 could matter depends on whether native PSMG3-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PSMG3-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PSMG3-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/PSMG3-AS1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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