Seroatlas · Human Serome Atlas

PRSS29P

Putative serine protease 29

Also known as: PRS29_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NIE9
Gene: PRSS29P
Canonical length: 313 aa

OverviewNCBI Gene

No narrative summary is available for PRSS29P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

313 residues, UniProt reviewed canonical sequence.

>A6NIE9|PRSS29P
     1  MPTTPDPGSE PPARTPRPPP LTPGLSPQPA LHALSPQLLL LLFLAVSSLG SCSTGSPVPV
    61  PENDLVGIVG GHNAPPGKWP WQVSLRVYSY HWASWAHICG GSLIHPQWVL TAAHCIFWKD
   121  TDPSIYRIHA GDVYLYGGRG LLNVSRIIVH PNYVTAGLGA DVALLQLEPH DLSNVRTVKL
   181  SPVSLELTPK DQCWVTGWGA IIRKESLPPP YRLQQASVQV LENAVCEQPY RNASGHTGDR
   241  QLILDDMLCA GSEGRDSCYG DSGGPLVCRL RGSWRLVGVV SWGYGCTLRD FPGVYTHVQI
   301  YVPWILQQVG ELP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PRSS29P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.33

OntologyGO

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PRSS29P as an antibody target. Whether an autoantibody or antibody against PRSS29P could matter depends on whether native PRSS29P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PRSS29P is annotated as secreted, so native PRSS29P circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label PRSS29P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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