Seroatlas · Human Serome Atlas

PRO1933

Putative uncharacterized protein PRO1933

Also known as: YJ001_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q9H354
Gene
PRO1933
Canonical length
126 aa

OverviewNCBI Gene

No narrative summary is available for PRO1933 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

126 residues, UniProt reviewed canonical sequence.

>Q9H354|PRO1933
     1  MNKHNLRLVQ LASELILIEI IPKLFLSQVT TISHIKREKI PPNHRKGILC MFPWQCVVYV
    61  FSNFVWLVIH RFSNGFIQFL GEPYRLMTAS GTHGRIKFMV DIPIIKNTQV LRIPVLKDPK
   121  MLSKKH

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PRO1933 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
1
Mean surface accessibility (rSASA)
0.57

OntologyGO

Cellular components

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PRO1933 as an antibody target. Whether an autoantibody or antibody against PRO1933 could matter depends on whether native PRO1933 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PRO1933 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PRO1933 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/PRO1933. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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