Seroatlas · Human Serome Atlas

PRO1854

Putative uncharacterized protein PRO1854

Also known as: YG001_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9UHT4
Gene: PRO1854
Canonical length: 67 aa

OverviewNCBI Gene

No narrative summary is available for PRO1854 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

67 residues, UniProt reviewed canonical sequence.

>Q9UHT4|PRO1854
     1  MNNHRANDKF FLYVCMYVCI REKILLYKTH WMTPIFLKVV INTRRIKHHF KIHVPSQFFI
    61  LITITKY

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PRO1854 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.53

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PRO1854 as an antibody target. Whether an autoantibody or antibody against PRO1854 could matter depends on whether native PRO1854 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PRO1854 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PRO1854 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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