PRO1716
Putative uncharacterized protein PRO1716
Also known as: YK039_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for PRO1716 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
43 residues, UniProt reviewed canonical sequence.
>Q9UHU1|PRO1716
1 MLTALGQVNN IQKEFTIKKT KQADHNLVAR IDEIQYVQGT INLLocalizationUniProt · AlphaFold · HPA
Whether an antibody against PRO1716 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.53
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads PRO1716 as an antibody target. Whether an autoantibody or antibody against PRO1716 could matter depends on whether native PRO1716 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
PRO1716 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label PRO1716 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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