Seroatlas · Human Serome Atlas

PRO0255

Putative uncharacterized protein PRO0255

Also known as: YE014_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q9UI72
Gene
PRO0255
Canonical length
69 aa

OverviewNCBI Gene

No narrative summary is available for PRO0255 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

69 residues, UniProt reviewed canonical sequence.

>Q9UI72|PRO0255
     1  MGMALELYWL CGFRSYWPLG TNAENEGNRK ENRRQMQSRN ERGCNVRQTK TYRDREADRH
    61  IHGIACLLF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PRO0255 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.58

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PRO0255 as an antibody target. Whether an autoantibody or antibody against PRO0255 could matter depends on whether native PRO0255 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PRO0255 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PRO0255 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/PRO0255. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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