PRDM10-DT
Putative uncharacterized protein encoded by LINC00167
Also known as: CK037_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for PRDM10-DT in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
147 residues, UniProt reviewed canonical sequence.
>Q96N53|PRDM10-DT
1 MTEGLFISCS AVRVKPNRRA GLRRRSPAFL LSANQKTRLF ALGSSPRCGP RANGEEASSC
61 AWVSRAPRAA CARAKPASRA PEGPVSRKTR GGEAALASAR PATDCLRSGL AVERRRKPNS
121 RPAPGVGSLP GSRPQDPQGA AGRRLSPLocalizationUniProt · AlphaFold · HPA
Whether an antibody against PRDM10-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.73
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads PRDM10-DT as an antibody target. Whether an autoantibody or antibody against PRDM10-DT could matter depends on whether native PRDM10-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
PRDM10-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label PRDM10-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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