Seroatlas · Human Serome Atlas

PPP1R2P1

Putative protein phosphatase inhibitor 2-like protein 1

Also known as: IPP2L_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96PQ5
Gene: PPP1R2P1
Canonical length: 205 aa

OverviewNCBI Gene

No narrative summary is available for PPP1R2P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

205 residues, UniProt reviewed canonical sequence.

>Q96PQ5|PPP1R2P1
     1  MAASTASQRP LKGILKDNTS TTSSMVASAE HPRGSVHEQL SKKSQKWDEM NILATYRPAD
    61  KDYGLMKIDE PSTPYHSTMG DDEDACSDTE TTEAMATDSL AKNLAAAEGL EPKYQVQEQE
   121  SSGEEDSDLS PEEREKKRQF EMRRTLHYNE GLNIKLARQL ISKDLHDDDK VEEMLETAHG
   181  ESMNTEESNQ GSTASDQQQN KSRSS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PPP1R2P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

OntologyGO

Biological processes

Molecular functions

protein phosphatase inhibitor activity

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PPP1R2P1 as an antibody target. Whether an autoantibody or antibody against PPP1R2P1 could matter depends on whether native PPP1R2P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PPP1R2P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PPP1R2P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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