Seroatlas · Human Serome Atlas

PP6455

Putative uncharacterized protein PP6455

Also known as: YS006_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8WZ26
Gene: PP6455
Canonical length: 134 aa

OverviewNCBI Gene

No narrative summary is available for PP6455 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

134 residues, UniProt reviewed canonical sequence.

>Q8WZ26|PP6455
     1  MCEQLVCIFT YAYLKINLTK ALGHHNPSYP VARAQPQTMF PSASECNAFP RVSKVPNRSG
    61  AAETALLVRV LPKPLKSQAS LLSLPFIHIT EQLSTHICVV LFKLFHVCLF TINNMNDCSM
   121  DAAERNAEGG LQLE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PP6455 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PP6455 as an antibody target. Whether an autoantibody or antibody against PP6455 could matter depends on whether native PP6455 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PP6455 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PP6455 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...