Seroatlas · Human Serome Atlas

PMS2P11

Putative postmeiotic segregation increased 2-like protein 11

Also known as: PM2PB_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q13670
Gene: PMS2P11
Canonical length: 270 aa

OverviewNCBI Gene

No narrative summary is available for PMS2P11 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

270 residues, UniProt reviewed canonical sequence.

>Q13670|PMS2P11
     1  MEKLSAASGY SDVTDSKAMG PLAVGCLTKC SHAFHLLCLL AMYCNGNKGP EHPNPGKPFT
    61  ARGFPASATF QTTPGPQASR GFQNPETLAD IPASPQLLTD GHYMTLPVSP DQLPCDDPMA
   121  GSGGAPVLRV GHDHGCHQQP RICNAPLPGP GPYRTEPAKA IKPIDRKSVH QICSGPVVLS
   181  LSTAVKELVE NSLDAGATNI DLKLKDYGMD LIEVSGNGCG VEEENFEGLM MSPFLPATSR
   241  RRLGLDWCLI TMGKSSRRPP TPTPEGPQSA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PMS2P11 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.56

OntologyGO

Molecular functions

kinase activity

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PMS2P11 as an antibody target. Whether an autoantibody or antibody against PMS2P11 could matter depends on whether native PMS2P11 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PMS2P11 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PMS2P11 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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