Seroatlas · Human Serome Atlas

PLAC4

Placenta-specific protein 4

Also known as: PLAC4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8WY50
Gene: PLAC4
Canonical length: 150 aa

OverviewNCBI Gene

No narrative summary is available for PLAC4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

150 residues, UniProt reviewed canonical sequence.

>Q8WY50|PLAC4
     1  MKELLRLKHC KHLLTTHVHS PWTPSLTLTP SLLTLDTLTH PRHRHSSPWT PHSAPWTPSL
    61  TLDTFTHPDT LTHPGHPHSP WIPSLLTLDT LTHPGYPHSS PWTLSLTLTP SILTLDSLTP
   121  HPGLPHSSPW TPSLLILDTL TQPGHPHSSP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PLAC4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.51

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PLAC4 as an antibody target. Whether an autoantibody or antibody against PLAC4 could matter depends on whether native PLAC4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PLAC4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PLAC4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...