Seroatlas · Human Serome Atlas

PIN1P1

Putative PIN1-like protein

Also known as: PINL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: O15428
Gene: PIN1P1
Canonical length: 100 aa

OverviewNCBI Gene

No narrative summary is available for PIN1P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

100 residues, UniProt reviewed canonical sequence.

>O15428|PIN1P1
     1  MADEEKLPPG WEKRMSRPSG RGYYFNHITN PSQWERPSGN SSSGGKIWQG EPARVRRSHL
    61  LVKPVKAALD LAAGNHPDQG GGPGADQRLH PEDQGRREGL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against PIN1P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads PIN1P1 as an antibody target. Whether an autoantibody or antibody against PIN1P1 could matter depends on whether native PIN1P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

PIN1P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label PIN1P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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