Seroatlas · Human Serome Atlas

P0C880

Putative uncharacterized protein FLJ40606

Also known as: YT014_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C880
Gene: P0C880
Canonical length: 135 aa

OverviewNCBI Gene

No narrative summary is available for P0C880 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

135 residues, UniProt reviewed canonical sequence.

>P0C880|P0C880
     1  MAAATETGQA AVPSRKRRRG RRPPASDPQT LARLAAGPWL PGTLTCPERT GGDAATRSAR
    61  PPVLPPPPRP PQRRCRHLVS RAGTPRCACA GTASEGPRRG RAAILSVAGS AGSSHPACFR
   121  PPPLLPIRPC CSLWR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against P0C880 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads P0C880 as an antibody target. Whether an autoantibody or antibody against P0C880 could matter depends on whether native P0C880 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

P0C880 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label P0C880 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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