Seroatlas · Human Serome Atlas

P0C879

Putative uncharacterized protein FLJ43185

Also known as: YJ018_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C879
Gene: P0C879
Canonical length: 139 aa

OverviewNCBI Gene

No narrative summary is available for P0C879 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

139 residues, UniProt reviewed canonical sequence.

>P0C879|P0C879
     1  MYNPWQVGAS LAPARAGPRP FPTPRARPPD CSGGHAPSGF PALGLRTAQR PRPFSSSPRS
    61  ASGRLRGPRP VARGPAHSSS PTGLPAYLPP AAALDSQTSA PTVSPVTRPR VVARGKTPRV
   121  SLAGLETLSS LLHQQQLFD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against P0C879 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.71

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads P0C879 as an antibody target. Whether an autoantibody or antibody against P0C879 could matter depends on whether native P0C879 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

P0C879 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label P0C879 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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