Seroatlas · Human Serome Atlas

OR8U8

Olfactory receptor 8U8

Also known as: OR8U8_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C7N1
Gene: OR8U8
Canonical length: 319 aa

OverviewNCBI Gene

No narrative summary is available for OR8U8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

319 residues, UniProt reviewed canonical sequence.

>P0C7N1|OR8U8
     1  MAHINCTQAT EFILVGLTDH QELKMPLFVL FLSIYLFTVV GNLGLILLIR ADTSLNTPMY
    61  FFLSNLAFVD FCYSSVITPK MLGNFLYKQN VISFDACATQ LGCFLTFMVS ESLLLASMAY
   121  DRYVAICNPL LYMVVMTPGI CIQLVAVPYS YSFLMALFHT ILTFRLSYCH SNIVNHFYCD
   181  DMPLLRLTCS DTRFKQLWIL ACAGITFICS VLIVFVSYMF IIFAILRMSS AEGRRKAFST
   241  CSSHMLAVTI FYGTLIFMYL QPSSSHSLDA DKMASVFYTV IIPMLNPLIY SLRNKDVKDA
   301  LKKVIINRNH AFIFLKLRK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR8U8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.28

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR8U8 as an antibody target. Whether an autoantibody or antibody against OR8U8 could matter depends on whether native OR8U8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR8U8 is annotated at the cell surface, where native OR8U8 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR8U8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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