Seroatlas · Human Serome Atlas

OR8J2

Olfactory receptor 8J2

Also known as: OR8J2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8NGG1
Gene
OR8J2
Canonical length
315 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR8J2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

315 residues, UniProt reviewed canonical sequence.

>Q8NGG1|OR8J2
     1  MASGNLTWVT EFILVGVSDD PELQIPLFLV FLVLYLLTVA GNLGIITLTS VDPQLQTPMY
    61  FFLRHLAIIN LCNSTVVAPK MLVNFLVTKK TISYYGCAAQ LGGFLVFIVA EIFTLAAMAY
   121  DRYVAIWSPL LYAVVVSPKV CRLLVSLTYL QSLITALTVS SCVFSVSYCS SNIINHFYCD
   181  DVPLLALSCS DTYIPETAVF IFSGTNLLFS MIVVLISYFN IVITILRIRS SEGRQKAFST
   241  CASHMIAVVV FYGTLLFMYL QPRSNHSLDT DKMASVFYTL VIPVLNPLIY SLRNKNVKDA
   301  LKRFLDNPCR SLKLM

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR8J2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.27
Highest tissue expression
0 nTPM

Expression across tissuesHPA

Tissue

  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM
  • cerebral cortex: 0 nTPM

Single-cell type

  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM
  • astrocytes: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • white matter: 0.2 nTPM
  • spinal cord: 0.1 nTPM
  • amygdala: 0 nTPM
  • basal ganglia: 0 nTPM
  • cerebellum: 0 nTPM
  • cerebral cortex: 0 nTPM

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR8J2 as an antibody target. Whether an autoantibody or antibody against OR8J2 could matter depends on whether native OR8J2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR8J2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label OR8J2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR8J2. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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