OR8G3
Olfactory receptor 8G3
Also known as: OR8G3_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for OR8G3 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
310 residues, UniProt reviewed canonical sequence.
>P0DMU2|OR8G3
1 MDPGNHSSVT ESILAGLSEQ PELQLRLFLL FLGICVVTVV GNLGMITLIG LSSHLHTPMY
61 YFLSSLSFID FCHSTVITPK MLVNFATEKN IISYPECMAQ LYLFSIFAIA ECHMLAAMAY
121 DCYVAICSPL LYNVIMSYHH CFWLTVGVYI LGILGSTIHT SFMLRLFLCK TNVINHYFCD
181 LFPLLGLSCS STYINELLVL VLSAFNILMP ALTILASYIF IIASILRIHS TEGRSKAFST
241 CSSHILAVAV FFGSAAFMYL QPSSVSSMDQ RKVSSVFYTT IVPMLNPLIY SLRNKDVKLA
301 VKKILHQTACLocalizationUniProt · AlphaFold · HPA
Whether an antibody against OR8G3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 7
- Mean surface accessibility (rSASA)
- 0.28
OntologyGO
Biological processes
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads OR8G3 as an antibody target. Whether an autoantibody or antibody against OR8G3 could matter depends on whether native OR8G3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
OR8G3 is annotated at the cell surface, where native OR8G3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label OR8G3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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