OR8G2P
Olfactory receptor 8G2
Also known as: O8G2P_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- Q6IF36
- Gene
- OR8G2P
- Canonical length
- 304 aa
- Protein class
- Predicted membrane proteins
OverviewNCBI Gene
No narrative summary is available for OR8G2P in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
304 residues, UniProt reviewed canonical sequence.
>Q6IF36|OR8G2P
1 MVFLSSVETD QRKMSAGNHS SVTEFILAGL SEQPELQLRL FLLFLGIYVV TVVGNLSMIT
61 LIGLSSHLHT PMYYFLSGLS FIDLCHSTII TPKMLVNFVT EKNIISYPEC MTQLYFFLIF
121 AIAECHMLAV TAYDRYVAIC SPLLYNVIMS YHHCFWLTVG VYVLGILGST IHTGFMLRLF
181 LCKTNVINHY FCDLFPLLGL SCSSTYINEL LVLVLSAFNI LTPALTILAS YIFIIASILR
241 IRSTEGRSKA FSTCSSHILA VAVFFGSAAF MYLQPSSVSS MDQRKVSSVF YTTIVPMLNP
301 QSIALocalizationUniProt · AlphaFold · HPA
Whether an antibody against OR8G2P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 7
- Mean surface accessibility (rSASA)
- 0.28
- Highest tissue expression
- 0 nTPM
Expression across tissuesHPA
Tissue
- adipose tissue: 0 nTPM
- adrenal gland: 0 nTPM
- appendix: 0 nTPM
- bone marrow: 0 nTPM
- breast: 0 nTPM
- cerebral cortex: 0 nTPM
Single-cell type
- early primary spermatocytes: 0.1 nCPM
- adipocytes: 0 nCPM
- adrenal cortex cells: 0 nCPM
- adrenal medulla cells: 0 nCPM
- alveolar cells type 1: 0 nCPM
- alveolar cells type 2: 0 nCPM
Immune cell
- basophil: 0 nTPM
- classical monocyte: 0 nTPM
- eosinophil: 0 nTPM
- gdT-cell: 0 nTPM
- intermediate monocyte: 0 nTPM
- MAIT T-cell: 0 nTPM
Brain region
- hypothalamus: 0.3 nTPM
- cerebral cortex: 0.2 nTPM
- basal ganglia: 0.1 nTPM
- amygdala: 0 nTPM
- cerebellum: 0 nTPM
- choroid plexus: 0 nTPM
OntologyGO
Biological processes
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads OR8G2P as an antibody target. Whether an autoantibody or antibody against OR8G2P could matter depends on whether native OR8G2P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
OR8G2P is annotated at the cell surface, where native OR8G2P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label OR8G2P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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