Seroatlas · Human Serome Atlas

OR5H8

Olfactory receptor 5H8

Also known as: OR5H8_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0DN80
Gene
OR5H8
Canonical length
308 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR5H8 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

308 residues, UniProt reviewed canonical sequence.

>P0DN80|OR5H8
     1  MDDENATLLT EFVLTGLTYQ SEWKIPLFLA FLVIYLITIM ANLGLIAVIW KDSHLHIPMY
    61  LFLGSLAFVD AWLSSSVTPK MLISFLAKSM IISVSECKIQ FFSFGISGTT ECFLLATMAY
   121  DRYVAICKPL LYPVIMTNGL CIWLLVLSFI GGFLHALIHE GILFRLTFCN SNIIHHFYCD
   181  IIPLLKISCT DPSINFLMLF ILSGSIQVFT ILTVLVSYTF VLFTILKKKA KDIRKAFSTC
   241  GAHLLSVSLY YGPLLFMYVH PASPQADDQD MVESLFYTVI IPFLNPIIYS LRNKQVIDSL
   301  TKTLKGNV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR5H8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.26
Highest tissue expression
0.1 nTPM

Expression across tissuesHPA

Tissue

  • testis: 0.1 nTPM
  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM

Single-cell type

  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM
  • astrocytes: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • amygdala: 0 nTPM
  • basal ganglia: 0 nTPM
  • cerebellum: 0 nTPM
  • cerebral cortex: 0 nTPM
  • choroid plexus: 0 nTPM
  • hippocampal formation: 0 nTPM

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR5H8 as an antibody target. Whether an autoantibody or antibody against OR5H8 could matter depends on whether native OR5H8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR5H8 is annotated at the cell surface, where native OR5H8 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR5H8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR5H8. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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