Seroatlas · Human Serome Atlas

OR5AL1

Olfactory receptor 5AL1

Also known as: O5AL1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0C617
Gene
OR5AL1
Canonical length
329 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR5AL1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

329 residues, UniProt reviewed canonical sequence.

>P0C617|OR5AL1
     1  MCALKGFLEE NFYTYSVAKG NHSTVYEFIL LGLTDNAELQ VTLFGIFLVV YLASFMGNFG
    61  LIMLIQISPQ LHTPMYFFLS HLAFVDFSFT SSVAPNTLVN FLCEVKSITF YACAIQVCCF
   121  ITFVVCELYL LSIMAYDRYV AICNPLLYVI LIPRKLCIKL IASTYVYGFT VGLVQTVATS
   181  YLSFCDSNVI NHFYHDDVPL VALACSDTHV KELMLLIIAG FNTLCSLVIV LISYGFIFFA
   241  ILRIHSAEGR QKAFSTSASH LTSITIFYGT IIFMYPQPKS SHSLNMDKVA SVFNVVVIPT
   301  LNPLIYSLRN QEVKNALKRI IEKLCLAVK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR5AL1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.3
Highest tissue expression
0 nTPM

Expression across tissuesHPA

Tissue

  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM
  • cerebral cortex: 0 nTPM

Single-cell type

  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM
  • astrocytes: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • amygdala: 0 nTPM
  • basal ganglia: 0 nTPM
  • cerebellum: 0 nTPM
  • cerebral cortex: 0 nTPM
  • choroid plexus: 0 nTPM
  • hippocampal formation: 0 nTPM

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR5AL1 as an antibody target. Whether an autoantibody or antibody against OR5AL1 could matter depends on whether native OR5AL1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR5AL1 is annotated at the cell surface, where native OR5AL1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR5AL1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR5AL1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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