Seroatlas · Human Serome Atlas

OR5AK3P

Olfactory receptor 5AK3

Also known as: O5AK3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8NH89
Gene
OR5AK3P
Canonical length
298 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR5AK3P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

298 residues, UniProt reviewed canonical sequence.

>Q8NH89|OR5AK3P
     1  MGRGNSTEVT EFHLLGFGVQ HEFQHVLFIV LLLIYVTSLI GNIGMILLIK TDSRLQTPMY
    61  FFPQHLAFVD ICYTSAITPK MLQSFTEENN LITFRGCVIQ FLVYATFATS DCYLLAIMAM
   121  DCYVAICKPL RYPMIMSQTV YIQLVAGSYI IGSINASVHT GFTFSLSFCK SNKINHFFCD
   181  GLPILALSCS NIDINIILDV VFVGFDLMFT ELVIIFSYIY IMVTILKMSS TAGRKKSFST
   241  CASHLTAVTI FYGTLSYMYL QPQSNNSQEN MKVASIFYGT VIPMLNPLIY SLRNKEGK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR5AK3P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.28
Highest tissue expression
0.7 nTPM

Expression across tissuesHPA

Tissue

  • spleen: 0.7 nTPM
  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM

Single-cell type

  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM
  • astrocytes: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • white matter: 1.7 nTPM
  • medulla oblongata: 0.5 nTPM
  • spinal cord: 0.5 nTPM
  • midbrain: 0.4 nTPM
  • pons: 0.3 nTPM
  • thalamus: 0.3 nTPM

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR5AK3P as an antibody target. Whether an autoantibody or antibody against OR5AK3P could matter depends on whether native OR5AK3P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR5AK3P is annotated at the cell surface, where native OR5AK3P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR5AK3P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR5AK3P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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