OR4K3
Olfactory receptor 4K3
Also known as: OR4K3_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- Q96R72
- Gene
- OR4K3
- Canonical length
- 315 aa
- Protein class
- Predicted membrane proteins
OverviewNCBI Gene
No narrative summary is available for OR4K3 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
315 residues, UniProt reviewed canonical sequence.
>Q96R72|OR4K3
1 MAWSNQSAVT EFILRGLSSS LELQIFYFLF FSIVYAATVL GNLLIVVTIA SEPHLHSPMY
61 FLLGNLSFID MSLASFATPK MIADFLREHK AISFEGCMTQ MFFLHLLGGA EIVLLISMSF
121 DRYVAICKPL HYLTIMSRRM CVGLVILSWI VGIFHALSQL AFTVNLPFCG PNEVDSFFCD
181 LPLVIKLACV DTYILGVFMI STSGMIALVC FILLVISYTI ILVTVRQRSS GGSSKALSTC
241 SAHFTVVTLF FGPCTFIYVW PFTNFPIDKV LSVFYTIYTP LLNPVIYTVR NKDVKYSMRK
301 LSSHIFKSRK TDHTPLocalizationUniProt · AlphaFold · HPA
Whether an antibody against OR4K3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 7
- Mean surface accessibility (rSASA)
- 0.27
- Highest tissue expression
- 0 nTPM
Expression across tissuesHPA
Tissue
- adipose tissue: 0 nTPM
- adrenal gland: 0 nTPM
- appendix: 0 nTPM
- bone marrow: 0 nTPM
- breast: 0 nTPM
- cerebral cortex: 0 nTPM
Single-cell type
- early spermatids: 0.1 nCPM
- adipocytes: 0 nCPM
- adrenal cortex cells: 0 nCPM
- adrenal medulla cells: 0 nCPM
- alveolar cells type 1: 0 nCPM
- alveolar cells type 2: 0 nCPM
Immune cell
- basophil: 0 nTPM
- classical monocyte: 0 nTPM
- eosinophil: 0 nTPM
- gdT-cell: 0 nTPM
- intermediate monocyte: 0 nTPM
- MAIT T-cell: 0 nTPM
Brain region
- pons: 0.2 nTPM
- amygdala: 0 nTPM
- basal ganglia: 0 nTPM
- cerebellum: 0 nTPM
- cerebral cortex: 0 nTPM
- choroid plexus: 0 nTPM
OntologyGO
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads OR4K3 as an antibody target. Whether an autoantibody or antibody against OR4K3 could matter depends on whether native OR4K3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
OR4K3 is annotated at the cell surface, where native OR4K3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label OR4K3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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