Seroatlas · Human Serome Atlas

OR4A4P

Putative olfactory receptor 4A4

Also known as: OR4A4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NGN8
Gene: OR4A4P
Canonical length: 299 aa

OverviewNCBI Gene

No narrative summary is available for OR4A4P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

299 residues, UniProt reviewed canonical sequence.

>Q8NGN8|OR4A4P
     1  MEPRKNVTDF VLLGFTQNPK EQKVLFVMFL LFYILTMVGN LLIVVTVTVS ETLGSPMSFF
    61  LAGLTFIDII YSSSISPRLI SDLFFGNNSI SFQSFMAQLF IEHLFGGSEV FLLLVMAYDR
   121  YVAICKPLHY LVIMRQWVCV LLLVVSWVGG FLQSVFQLSI IYGLPFCGPN VIDHFFCDMY
   181  PLLKLACTDT HVIGLLVVAN GGLSCTIAFL LLLISYGVIL HSLKKLSQKG RQKAHSTCSS
   241  HITVVVFFFV PCIFMCARPA RTFSIDKSVS VFYTVITPML NPLIYTLRNS EMTSAMKKL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR4A4P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.26

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR4A4P as an antibody target. Whether an autoantibody or antibody against OR4A4P could matter depends on whether native OR4A4P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR4A4P is annotated at the cell surface, where native OR4A4P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR4A4P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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