Seroatlas · Human Serome Atlas

OR3A4P

Putative olfactory receptor 3A4

Also known as: OR3A4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P47883
Gene: OR3A4P
Canonical length: 348 aa

OverviewNCBI Gene

No narrative summary is available for OR3A4P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

348 residues, UniProt reviewed canonical sequence.

>P47883|OR3A4P
     1  MDLGNSGNDS VVTKFVLLGL TETAALQPIL FVIFLLAYVT TIGGTLSILA AILMETKLHS
    61  PMYFFLGNLS LPDVGCVSVT VPAMLSHFIS NDRSIPYKAC LSELFFFHLL AGADCFLLTI
   121  MAYDRYLAIC QSLTYSSRMS WGIQQALVGM SCVFSFTNAL TQTVALSPLN FCGPNVINHF
   181  YCDLPQPFQL SCSSVHLNGQ LLFVAAAFMG VAPLVLITVS YAHVAAAVLR IRSAEGRKKA
   241  FSTCSSHLTV VGIFYGTGVF SYTRLGSVES SDKDKGIGIL NTVISPMLNP LIYWTSLLDV
   301  GCISHCSSDA GVSPGPPVQS SLCCLQFTAL LSPPPGWGGL SPLNSHGL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR3A4P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.32

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 2% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR3A4P as an antibody target. Whether an autoantibody or antibody against OR3A4P could matter depends on whether native OR3A4P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR3A4P is annotated at the cell surface, where native OR3A4P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR3A4P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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