Seroatlas · Human Serome Atlas

OR1P1

Olfactory receptor 1P1

Also known as: OR1P1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8NH06
Gene
OR1P1
Canonical length
330 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR1P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

330 residues, UniProt reviewed canonical sequence.

>Q8NH06|OR1P1
     1  MGLTQDFFPP TSELLEGGNQ TSTFEFLLWG LSDQPQQQHI FFLLFLWMYV VTVAGNLLIV
    61  LAIGTDTHLH TPMYFFLASL SCADIFSTST TVPKALVNIQ TQSRSISYAG CLAQLYFFLT
   121  FGDMDIFLPA TMAYDRYVAI CHLLHYMMIM SLHRCAFLVT ACWTLTSLLA MTRTFLIFRL
   181  SLCSKILPGF FCDLGPLMKV SCSDAQVNEL VLLFLGGAVI LIPFMLILVS YIRIVSAILR
   241  APSAQGRRKA FSTCDSHLVV VALFFGTVIR AYLCPSSSSS NSVKEDTAAA VMYTVVTPLL
   301  NPFIYSMRNK DMKAAVVRLL KGRVSFSQGQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR1P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.31
Highest tissue expression
0 nTPM

Expression across tissuesHPA

Tissue

  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM
  • cerebral cortex: 0 nTPM

Single-cell type

  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM
  • astrocytes: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • thalamus: 0.2 nTPM
  • amygdala: 0.1 nTPM
  • basal ganglia: 0.1 nTPM
  • cerebellum: 0.1 nTPM
  • cerebral cortex: 0.1 nTPM
  • hippocampal formation: 0.1 nTPM

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR1P1 as an antibody target. Whether an autoantibody or antibody against OR1P1 could matter depends on whether native OR1P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR1P1 is annotated at the cell surface, where native OR1P1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR1P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR1P1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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