Seroatlas · Human Serome Atlas

OR1F12P

Putative olfactory receptor 1F12P

Also known as: OR1FC_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NHA8
Gene: OR1F12P
Canonical length: 337 aa

OverviewNCBI Gene

No narrative summary is available for OR1F12P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

337 residues, UniProt reviewed canonical sequence.

>Q8NHA8|OR1F12P
     1  MEGKNQTNIS EFLLLGFSSW QQQQVLLFAL FLCLYLTGLF GNLLILLAIG SDHCLHTPMY
    61  FFLANLSLVD LCLPSATVPK MLLNIQTQTQ TISYPGCLAQ MYFCMMFANM DNFLLTVMAY
   121  DRYVAICHPL HYSTIMALRL CASLVAAPWV IAILNPLLHT LMMAHLHFCS DNVIHHFFCD
   181  INSLLPLSCS DTSLNQLSVL ATVGLIFVVP SVCILVSYIL IVSAVMKVPS AQGKLKAFST
   241  CGSHLALVIL FYGAITGVYM SPLSNHSTEK DSAASVIFMV VAPVLNPFIY SLRNNELKGT
   301  LKKTLSRPGA VAHACNPSTL GGRGGWIMRS GDRDHPG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR1F12P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.3

OntologyGO

Biological processes

signal transduction

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR1F12P as an antibody target. Whether an autoantibody or antibody against OR1F12P could matter depends on whether native OR1F12P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR1F12P is annotated at the cell surface, where native OR1F12P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR1F12P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...