Seroatlas · Human Serome Atlas

OR1E3

Olfactory receptor 1E3

Also known as: OR1E3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8WZA6
Gene: OR1E3
Canonical length: 343 aa

OverviewNCBI Gene

No narrative summary is available for OR1E3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

343 residues, UniProt reviewed canonical sequence.

>Q8WZA6|OR1E3
     1  MMKKNQTMIS EFLLLGLPIQ PEQQNLFYAL FLAVYLTTLL GNLLVIVLIR LDSHLHMPMY
    61  LCLSNLSFSD LCFSSVTMPK LLQNMQSQNP SIPFADCLAQ MYFHLFYGVL ESFLLVVMAY
   121  HCYVAICFPL HYTTIMSPKC CLGLLTLSWL LTTAHATLHT LLMARLSFCA ENVIPHFFCD
   181  TSTLLKLACS NTQVNGWVMF FMGGLILVIP FLLLIMSCAR IVSTILRVPS TGGIQKAFST
   241  CGPHLSVVSL FYGTIIGLYL CPLTNHNTVK DTVMAVMYTG VTHMLNPFIY SLRNRDMRGN
   301  PGQSLQHKEN FFVFKIVIVG ILPLLNLVGV VKLIMKYHSK SVA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR1E3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.29

OntologyGO

Biological processes

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR1E3 as an antibody target. Whether an autoantibody or antibody against OR1E3 could matter depends on whether native OR1E3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR1E3 is annotated at the cell surface, where native OR1E3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR1E3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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